Augmentin 375 (Amoxicillin / Clavulanic Acid)
Augmentin 375 Tablet (Amoxicillin / Clavulanic Acid) belongs to a class of antibiotic medicines called penicillin. It is used to treat bacterial infections of the respiratory tract (bronchitis, pneumonia), genital and urinary tract (gonorrhoea, ), skin and soft tissue, ear (otitis media); nose, sinus, and throat (tonsillitis, sinusitis); heart (endocarditis), kidney, urethra or bladder, blood (septicemia), teeth and gums (abcesses), typhoid and paratyphoid fever.
Augmentin 375 is used to increase the effect of certain antibiotics (amoxicillin) to treat bacterial infections of the respiratory tract (bronchitis, pneumonia), urinary tract, ear, nose, sinus and throat, skin and soft tissues, bone and joints, and to prevent infections after surgery.
Generic Augmentin ? General information
Augmentin 375 is an unusual antibiotic of the broad-spectrum action. Most known antibacterial drugs contain only one active component. Often, using such drugs, bacteria develop a resistance and the efficiency of the treatment falls. In order to avoid this, it is enough to buy Augmentin 375 and the treatment of the severe infectious diseases will be more effective.
Augmentin contains two active components namely amoxicillin and clavulanic acid.
Augmentin 375 is very popular antibacterial drug which may destroy the most different morbific microorganisms. It provides a fast pharmacological action with bactericidal effect. The therapeutic effect appears because this component destroys the cell wall of bacteria and makes them vulnerable.
Bacteria die within a short period of time and the infection symptoms completely pass.
But the action of Amoxicillin is often bothered by components (b-lactamase) produced by these microbes. Due to this, many one-component antibiotics do not bring the needed results in the treatment of the infections. Clavulanic acid, as a component of Augmentin drug, provides a resistance of Amoxicillin to the influence of b-lactamase increasing its area of the action.
The combination of these two components provides the high efficiency.
How Augmentin 375 works?
Augmentin 375 kills bacteria by interfering with the production of the bacterial cell wall (outer coating of bacteria). As a result, the bacterial cell wall is weakened and ruptured, thereby killing the bacteria.
Clavulanic acid belongs to a group of medicines called beta-lactamase inhibitors. It blocks the activity of a chemical (beta-lactamase), which is secreted by bacteria to protect themselves from antibiotic drugs like amoxicillin, thereby allowing the antibiotics to act against the bacteria. It does not kill bacteria and is never used alone to treat infections.
How to take Generic Augmentin?
Use Augmentin as directed by your doctor.
Take Augmentin 375 by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
To clear up your infection completely, take Augmentin 375 for the full course of treatment. Keep taking it even if you feel better in a few days.
Does not use if you are allergic to any other penicillin antibiotic, have liver or kidney failure or mononucleosis.
Do not use the medicine if you have allergy to its components or another penicillin antibiotics, you have infectious mononucleosis, a history of liver problems or yellowing of the eyes or skin caused by Augmentin.
Interaction with other drugs
- Anticoagulants (eg, warfarin) because the risk of bleeding may be increased
- Probenecid because it may increase the amount of Augmentin in your blood
- Chloramphenicol, macrolide antibiotics (eg, erythromycin), sulfonamides (eg, sulfamethoxazole), or tetracycline antibiotics (eg, doxycycline) because they may decrease Augmentin 375 effectiveness
- Methotrexate because the risk of its side effects may be increased by Augmentin
- Live oral typhoid vaccine or hormonal birth control (eg, birth control pills) because their effectiveness may be decreased by Augmentin.
Common side effects
Vaginal itching, Diarrhoea, Nausea, Headache, Allergic reaction, Stomach pain, Vomiting, Vaginal discharge, Rash,
Frequently Asked Questions
Q: Is amoxicillin safe for infants, or during pregnancy, breast-feeding, or affect birth control?
A: Paediatric suspension of amoxicillin in the dosage as prescribed by the doctor is recommended for infants. Amoxicillin is generally regarded as a safe drug during pregnancy or breast feeding. However, it should be taken only after consulting the doctor and when potential benefits outweigh the involved risks. Amoxicillin may reduce the effect of the birth control pills.
Q: Does amoxicillin act against anaerobic bacteria?
A: Amoxicillin is active against aerobic as well as anaerobic bacterial infections.
Q: Does amoxicillin cause yeast infections?
A: Amoxicillin is a broad spectrum antibiotic and hence with prolonged use may also kill helpful bacteria in the body that keep the body?s yeast population in check, thereby causing yeast infections.
Q: Can I take amoxicillin for sore throat, cold, cough, flu, food poisoning, pseudomonas infection or virus infections?
A: Amoxicillin is only effective against bacterial infections not viruses. Food poisoning (due to Salmonella), pseudomonas infections, as well as sore throat, cold and cough caused due to bacteria can be treated with amoxicillin.
Q: Does amoxicillin cause constipation, drowsiness or headache?
A: No. Amoxicillin does not cause constipation, drowsiness or headache. However, consult your doctor if you experience such side effects.
Q: How long does novamoxin take to work?
A: Anywhere between one to seven days but it depends on the type of infection and its severity.
Q: Is novamoxin gluten free?
A: Novamoxin, which contains amoxicillin, is gluten free.
Q: Is antibiotic + clavulanic acid combination effective against STD, MRSA, or pseudomonas infections?
A: It is effective against s**ually transmitted diseases (STD) caused by bacteria and pseudomonas infections, but weakly effective against methicillin-resistant Staphylococcus aureus infections (MRSA).
Q: Is amoxicillin + clavulanic acid (Augmentin) safe in G6PD deficiency?
A: There are no confirmed studies about the safety of amoxicillin + clavulanic acid (Augmentin) in G6PD deficiency. Consult your doctor before use.
Q: Is amoxicillin + clavulanic acid (Augmentin) nephrotoxic?
A: If taken in appropriate dosage as prescribed by the doctor, Augmentin is not nephrotoxic.
Q: Does amoxicillin + clavulanic acid (Augmentin) contain sulfa?
A: No, amoxicillin + clavulanic acid (Augmentin) does not contain sulfa.
Q: Does amoxicillin + clavulanic acid (Augmentin) make you drowsy or tired?
A: No, amoxicillin + clavulanic acid (Augmentin) does not make you drowsy or tired if taken as prescribed.
We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.