Intalith CR 450 mg Tablet
Buy Intalith 450 mg Tablet, Lithium is used to treat and prevent mania (exaggerated emotions and over-excitability), hypomania (milder form of mania), bipolar diseases (mood changes with alternating periods of elation and depression), and aggressive and self-harming behavior when other drugs are not effective.
Lithium Carbonate ER Tablets Description
Lithium 450 mg carbonate extended-release tablets USP contain lithium carbonate USP, a white odorless alkaline powder with molecular formula Li2CO3 and molecular weight 73.89. Lithium is an element of the alkali metal group with atomic number 3, atomic weight 6.94 and an emission line at 671 nm on the flame photometer. Each light pink to pink colored circular, biconvex, film-coated, extended-release tablet contains 300 mg of lithium carbonate USP. This slowly dissolving film-coated tablet is designed to give lower serum lithium peak concentrations than obtained with conventional oral lithium dosage forms. Inactive ingredients consist of sodium chloride, povidone, sorbitol, sodium starch glycolate, sodium lauryl sulfate, calcium stearate VG, hypromellose, titanium dioxide, polyethylene glycol and iron oxide red.
Lithium 450 mg is used to treat and prevent mania (exaggerated emotions and over-excitability), hypomania (milder form of mania), bipolar diseases (mood changes with alternating periods of elation and depression), and aggressive and self-harming behavior when other drugs are not effective. It is sometimes used for treatment of low white blood count due to cancer treatment and improving urine output in patients suffering from excess antidiuretic hormone (ADH) disease.
How Lithium 450 mg works
Lithium 450 mg is a mood stabilizing drug. It works by interfering with the production and uptake of chemicals called neurotransmitters in the nerves, thereby restoring its balance in brain.
Common side effects
• Decreased memory,
• Decreased libido,
• Increased frequency of urination,
• Increased thirst,
• Fine hand tremors,
• Muscle weakness,
• Dry mouth,
• Weight gain,
Lithium 450 mg Clinical Pharmacology
Preclinical studies have shown that lithium alters sodium transport in nerve and muscle cells and effects a shift toward intraneuronal metabolism of catecholamines, but the specific biochemical mechanism of lithium action in mania is unknown.
Indications and Usage for Lithium 450 mg
Lithium 450 mg carbonate extended-release tablets USP are indicated in the treatment of manic episodes of Bipolar Disorder. Bipolar Disorder, Manic (DSM-IV) is equivalent to Manic Depressive illness, Manic, in the older DSM-II terminology. Lithium carbonate extended-release tablets USP are also indicated as a maintenance treatment for individuals with a diagnosis of Bipolar Disorder. Maintenance therapy reduces the frequency of manic episodes and diminishes the intensity of those episodes which may occur.
Typical symptoms of mania include pressure of speech, motor hyperactivity, reduced need for sleep, flight of ideas, grandiosity, elation, poor judgment, aggressiveness, and possibly hostility. When given to a patient experiencing a manic episode, lithium may produce a normalization of symptomatology within 1 to 3 weeks.