Pyzina 500 mg (Pyrazinamide)
Pyzina 500 (Pyrazinamide), Pyrazinamide Tablets is used in combination with other antibiotics for the treatment of tuberculosis (TB ? a serious infection caused by bacteria that affects the lungs and in certain cases other parts of the body). Pyzina 500 is an antibiotic. It kills or stops growth of bacteria that causes tuberculosis (Mycobacterium tuberculosis).
Uses
Pyrazinamide is used in combination with other antibiotics for the treatment of tuberculosis (TBÂ a serious infection caused by bacteria that affects the lungs and in certain cases other parts of the body).
How to Pyrazinamide (Pyzina 500) work?
Pyrazinamide is an antibiotic. It kills or stops growth of bacteria that causes tuberculosis (Mycobacterium tuberculosis).
What is Pyrazinamide?
Pyrazinamide is an antibiotic medication prescribed mainly for the treatment of tuberculosis (TB). It may also be used for treatment of other infections. Pyzina 500 is available under several trade names, one of which is Pyzina (made by Lupin).
Important Information about Pyrazinamide
• Do not take Pyzina 500 if you have a known allergy to it. Tell your doctor about it. Also, let your doctor know in advance if you have any of the following conditions: liver disease, gout, kidney disease, or diabetes mellitus.
• Pyrazinamide is an FDA pregnancy category C drug. Do not take this medication without your doctor?s advice if you are pregnant or breast feeding. This medication can pass into breast milk and harm a nursing baby.
• You must complete the full course of Pyrazinamide. If you do not complete the medication course as prescribed, you may get a drug resistant infection which will be difficult to treat with common antibiotics.
Before taking Pyrazinamide
Pyrazinamide (Pyzina) is a prescription-only drug and available only with a doctor?s prescription. Before taking it, you must consult a doctor. Let him or her know in advance if you have any of the following conditions: liver disease, gout, kidney disease, or diabetes mellitus.
How should I take Pyrazinamide?
Take Pyzina 500 strictly as prescribed by your doctor. Do not make any changes in using the medication without his or her advice. All medications come with a patient leaflet. Follow the instructions in them if you have any doubt. However, remember that your doctor?s advice overrides everything else.
Dosage Instructions:
What happens if I miss a dose of Pyrazinamide?
Don?t miss a single dose of Pyrazinamide. But if you do miss a dose for some reasons, take it as soon as you remember it. However, forget about the missed dose if the time for the next dose is near. Don?t take multiple doses close to each other to compensate for the missed dose as that will lead to extra medicine in your body at one time which can be.
What if I overdose?
Get immediate medical attention in case of an overdose or call the Doctor Immediately.
What should I avoid while taking Pyrazinamide?
Follow any diet, drug or activity restrictions advised by your doctor while taking Pyrazinamide.
Pyrazinamide Side Effects
• Jaundice
• Hepatitis (viral infection of liver)
• Increased liver enzymes
• Joint pain
Pyrazinamide Dosing Instructions:
Pyrazinamide dosage may depend on a range of factors like seriousness of the condition, age, s**, or drug allergies among a host of several other factors.
Interaction with other drugs
There are some drugs which can interact with Pyrazinamide or vice versa. This medication can reduce the effects of allopurinol. Let your doctor know in advance if you are using this medication or any other medicines. Pyrazinamide may also affect Acetest and Ketostix urine tests for ketones. Drugs other than those mentioned here may also interact with pyzina 500. Do not start a new medication without going to a doctor or without proper medical advice.
FAQs
Q: Is pyrazinamide safe in pregnancy?
A: Studies of pyrazinamide in animals have shown risk to fetus. There are no adequate studies of pyrazinamide in pregnant women. Its use in pregnant women is recommended only if the potential benefits outweigh the potential risks. Do consult your doctor before taking Pyzina 500 if you are pregnant or planning to become pregnant.
Q: What is pyrazinamide and what is it used for?
A: Pyrazinamide is an antibiotic. It is used in combination with other antibiotics in the treatment of tuberculosis.
Q: Is pyrazinamide bactericidal?
A: Pyrazinamide is both a bacteriostatic and a bactericidal antibiotic. It stops the growth of bacteria (bacteriostatic) in certain cases and kills (bactericidal) the tuberculosis causing bacteria in other cases.
Q: How does pyrazinamide work/treat tuberculosis?
A: Pyrazinamide kills or stops growth of bacteria that causes tuberculosis (Mycobacterium tuberculosis). The exact mechanism of action for pyrazinamide is not known.
Q: How does pyrazinamide cause hyperuricemia and gout?
A: Following oral intake of pyrazinamide, it gets converted in the body to pyrazinoic acid (active chemical form of pyrazinamide). Pyrazinoic acid blocks the excretion of urates (salt form of uric acid) by the kidneys. This causes an increase in blood levels of uric acid (hyperuricemia). Excess uric acid accumulation between joints causes pain, swelling, redness and stiffness in joints (gout).
