Trajenta 5 mg (Linagliptin)
Uses of Trajenta 5 mg (Linagliptin)
Trajenta 5 mg is used alone or in combination with other drugs to treat type 2 diabetes mellitus.
How Dose Trajenta 5 mg (Linagliptin) works
Trajenta 5 mg is an oral antidiabetic belongs to a class of medications called dipeptidyl peptidase-4 (DPP-4) inhibitors. It acts by inhibiting the enzyme (dipeptidyl peptidase-4; DPP-4) which prevents the breakdown of substances called as incretins, ultimately increasing the production of insulin that reduces blood glucose level at fasting and after intake of food.
What is linagliptin?
Linagliptin is an oral diabetes medicine that helps control blood sugar levels. It works by regulating the levels of insulin your body produces after eating. It is used together with diet and exercise to treat type 2 diabetes. It is not for treating type 1 diabetes. It may also be used for purposes not listed in this medication guide.
What is the most important information I should know about linagliptin?
Do not use this medicine if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).
Linagliptin is not for treating type 1 diabetes.
What should I discuss with my healthcare provider before taking linagliptin?
You should not use this medicine if you are allergic to linagliptin, or if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).
To make sure linagliptin is safe for you, tell your doctor if you have:
• High triglycerides (a type of fat in the blood);
• A history of alcoholism; or
• If you are using insulin, or taking other oral diabetes medication.
Linagliptin is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether linagliptin passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
This medicine is not approved for use by anyone younger than 18 years old.
How should I take linagliptin?
Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.
You may take this medicine with or without food. Follow your doctor?s instructions.
Your blood sugar will need to be checked often, and you may need other blood tests at your doctor?s office.
Low blood sugar (hypoglycemia) can happen to everyone who has diabetes. Symptoms include headache, hunger, sweating, pale skin, irritability, dizziness, feeling shaky, or trouble concentrating. Always keep a source of sugar with you in case you have low blood sugar. Sugar sources include fruit juice, hard candy, crackers, raisins, and non-diet soda. Be sure your family and close friends know how to help you in an emergency.
If you have severe hypoglycemia and cannot eat or drink, use a glucagon injection. Your doctor can prescribe a glucagon emergency injection kit and tell you how to use it.
Check your blood sugar carefully during times of stress, travel, illness, surgery or medical emergency, vigorous exercise, or if you drink alcohol or skip meals. These things can affect your glucose levels and your dose needs may also change. Do not change your medication dose or schedule without your doctor?s advice.
Linagliptin is only part of a treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care. Follow your doctor?s instructions very closely.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention, Just in case if you?re taking an additional dose, consult your doctor and do as instructed.
What should I avoid while taking linagliptin?
Follow your doctor?s instructions about any restrictions on food, beverages, or activity.
Common side effects
• Pancreatic inflammation,
• Angioedema (swelling of deeper layers of skin),
• Fall in blood sugar level,
Expert advice for Trajenta
Do not start or continue linagliptin and consult your doctor:
• If you are allergic to linagliptin or to any medicine from the same group (DPP-4 inhibitors).
• If you have type 1 diabetes or if you have serious complication of diabetes where high levels of blood acids called ketones are produced in your body (diabetic ketoacidosis).
• If you are taking insulin or other antidiabetic drug known as a sulphonylurea, your doctor may reduce the dose of your medicines, as it may otherwise cause excessively low blood glucose (hypoglycemia).
• If you are already being treated with insulin (medicine to lower blood sugar levels) and have severe kidney disease.
• If you have/had a disease of the pancreas.
• Do not substitute it with insulin, if you are on insulin.
Q: Is linagliptin better than sitagliptin?
A: Linagliptin and sitagliptin belong to same class of drugs (DPP-4 inhibitor) with similar action, but their effect may vary upon individual response.
Q: Is linagliptin available in India?
A: Yes, linagliptin is available in India with brand name as Trajenta.
Q: Is linagliptin generic?
A: Linagliptin is generic name; however, linagliptin is not available in a generic form.
Q: Is linagliptin safe?
A: Linagliptin is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q: How is linagliptin excreted?
A: Linagliptin is mainly excreted in stools and less in urine.
Q: What is linagliptin and for which treatment used for?
A: Linagliptin belongs to a group of medications called dipeptidyl peptidase-4 (DPP-4) inhibitors, and used in addition to diet and exercise for the treatment of type-2 diabetes.
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